CIRM HIV/AIDS Research Grantees

CIRM is the California Institute of Regenerative Medicine.  HIV/AIDS Fact Sheet

Mark Anderson University of California, San Francisco Generation of a functional thymus to induce immune tolerance to stem cell derivatives $1,191,000
John Zaia City of Hope A Phase I, Open-Label Study to Assess the Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells with Escalating Doses of Busulfan in HIV-1 (R5) Infected Subjects with Suboptim $5,583,438
John Zaia City of Hope The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,000,000
Paula Cannon University of Southern California Site-specific gene editing in hematopoietic stem cells as an anti-HIV therapy $1,499,400
Mehrdad Abedi University of California, Davis Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-selected CD34+ Cells in AIDS lymphoma patients $8,435,822
David DiGiusto City of Hope Development of RNA-based approaches to stem cell gene therapy for HIV $3,097,160
John Zaia City of Hope ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969
Irvin Chen University of California, Los Angeles HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Irvin Chen University of California, Los Angeles Genetic modification of the human genome to resist HIV-1 infection and/or disease progression $616,800
Zack Jerome University of California, Los Angeles Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
Geoff Symonds Calimmune, Inc. GENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE $8,278,722
Mark Anderson University of California, San Francisco Stem cell differentiation to thymic epithelium for inducing tolerance to stem cells $1,314,089
Mehrdad Abedi University of California, Davis RUNNING TITLE: Stem Cell Gene Therapy for HIV in AIDS Lymphoma Patients $66,880
Zack Jerome University of California, Los Angeles Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
Irvin Chen University of California, Los Angeles HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
Total:

$71,357,953.00